I did, but with RADDS ( 6 driver ports ).
For Duet you'd need to add another external driver ( eg. on ebay ) or get a DuetX2-X5 extension board.
The X2 and X5 have the huge advantage of the TMC2660 drivers and software controlled current.
I'm not sure if the extruder mixing would work with one keyes-driver being different. ( But I'd try for sure, before I buy a X2 )